Searchable abstracts of presentations at key conferences in endocrinology

ea0015p70 | Clinical practice/governance and case reports | SFEBES2008

Lithium blocks the mineralocorticoid action of fludrocortisone in Addison’s disease both for replacement and in the treatment of Addisonian crisis

Prentice Malcolm , Russell Gerald

A 44-year-old Caucasian female eight years previously had been diagnosed auto immune Addison’s disease and started on replacement with hydrocortisone 30 mg daily in divided doses and fludrocortisone 0.1 mg was started on lithium carbonate. One month later when her lithium level was 1.0 mmol/l she was noted to have a sodium of 129 mmol/l, potassium of 5.2 mmol/l and fludrocortisone was increased to 0.3 mg om. Over the next year as her lithium dose was increased as her reni...